Camelia Shiseido

Defend Beauty

Defend beauty. Give your skin the strength it needs.
Skin defense system is fundamental for healthy-looking skin.

Beauty is a feeling that is shared among all people, no matter what
their culture. It is a positive force that we are inspired by.




What is Ultimune?

Shiseido has been researching skin defense for over 20 years.

Ultimune is a product that embodies Shiseido skincare. It strengthens the skin’s natural powers of defense, enabling it to build its own beauty.
It enhances the benefits of skincare routines that follow. Smooth, supple, and with less fine lines - skin radiates with a healthy look.

What is skin defense?

Just like your body,
your skin has its own defense system.

Want to know more? Learn More

The skin is a dynamic organ that contains different cells that are activated when the tissue is under attack by invading external aggressors (such as pathogens, pollution). As your skin is the first defense against irritants like time, exposure and stress, the condition of your skin’s defensive system is critical towards self-repair.

Langerhans cells (present in the epidermis) play a crucial role in skin’s protection, triggering defenses against stressors to achieve skin's highest beauty potential. When the function of Langerhans cells declines due to UV rays, dryness and emotional stress, it can cause skin concerns to appear such as loss of firmness, and wrinkles and dark spots appear.

After more than 20 years of research, Shiseido has determined the effect skin’s defensive system has on the condition of the skin and created a complex that successfully supports Langerhans cells.*

*in vitro test




Exclusively developed ingredients to defend beauty.

Ultimune ComplexTMComprising of superior, originally-developed and naturally occurring ingredients, Ultimune ComplexTM nourishes and shields your skin, and defends against the harmful effects and external hazards.

Defends your skin against oxidation and harmful substances with the power of plants.

Ginko Biloba, Perilla (Eastern herb), Wild Thyme (Western herb) ‒ known as an anti-oxidant, as well as other various effects.

Fragrance Effect

Rose, Lotus – For a feeling of relaxation.

The Impact of


Your skin texture is smoother and more supple.*

“This is the first time I’ve used a skincare product and noticed visible results. I like how easily it is applied and how silky it feels. I have definitely seen the texture and plumpness of my skin improve after use.”

In 1 Weekarrow

Your skin tone is clearer and more radiant.*

“My skin has obviously responded to using this product. From daily application, I’ve noticed my cheeks look less sullen when I wake up, and my skin tone is definitely brighter.”

In 4 Weeks

Your skin contour appears firmer and more resilient.*
Want to continue using this product.*
Feel skin become strong.*
Want to add this product to my current facial skincare regimen.*

*Tested on over 220 women, self-evaluation.

The Benefits of
Combined Use

Combine the power of Ultimune with our Bio Performance and double the protection for your skin. Enjoy the benefits morning and night for beautiful, visible results.


After 4 weeks using Bio Performance and Ultimune together.

the hydration for your skin*
Advanced Super Revitalizing Cream
*Instrumental test on 30 women - 4 weeks - Ultimune + cream vs cream

After 4 weeks using Bio Performance and Ultimune together.

women consider their skin smoother**
Advanced Super Restoring Cream
**Auto-evaluation test on 219 women - 4 weeks - Ultimune + cream

After using Ultimune with a multi-functional serum for 2 weeks:

Skin appears more radiant and youthful.***

Glow Revival Serum
felt they were more powerful when used together.***
felt the multi-functional serum’s repairing effects had been enhanced.***
***The test items used were Ultimune Power Infusing Concentrate and Bio-Performance Glow Revival Serum, as Shiseido’s standard multi-functional serum, for a combined usage test. Test on 110 women, self-evaluation.

Ultimune as a Daily Ritual


Apply twice daily, morning and evening, after cleansing and balancing skin.


Press the pump twice to dispense serum into the palm of hand.


When used with other serums, apply Ultimune first.

For the Eyes: Ultimune Eye

The area around the eye contains the most delicate skin on the entire human face. It requires special care.

Ultimune Power Infusing Eye Concentrate

Shiseido developed ImuMoisture ExtractTMan ingredient unique to Ultimune Eye that protects the precious eye skin for a fully nourished eye area.

Ultimune Eye